CLL	Chronic Lymphocytic Leukemia
OR	Overal response rate
CR	Complete Response
CRi	Complete Response with incomplete bone marrow recovery
PR	Partial response
PR-L	Partial response with Lymphocytosis
MRD	Minimal residual disease
UMRD	Undetectable minimal residual disease
PFS	Progression free survival
OS	Overall survival
IGHV	ImmunoGlobulin heavy-chain variable region gene;
AE	Adverse event
GIMEMA	Gruppo Italiano Malattie EMatologiche dell’Adulto
B2M	β2-Mmcroglobulin
LDH	Lactate DeHydrogenase
CIRS	Cumulative Illness Rating Scale score
CrCl	Creatinine clearance
ECOG PS	Eastern Cooperative Oncology Group performance-status
FISH	Fluorescence in situ hybridization
TP53	Tumor protein p53
ITT	Intention to treat
EOCT	End of combination therapy
Ig	Immunoglobulins