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. 2021 Dec 21;19(1):5. doi: 10.3390/ijerph19010005

Table 2.

Psychiatric characteristics and substance use patterns by chronic pain status.

Total (N = 828)
N (%)
Participants with Chronic Pain
N (%)
Participants without Chronic Pain
N (%)
p a
Major Depressive Episode b 319 (39) 205 (46) 114 (30) <0.001
Manic or Hypomanic Episode b 131 (16) 82 (18) 49 (13) 0.034
Post-traumatic Stress Disorder b (N = 827) 214 (26) 139 (31) 75 (20) <0.001
Panic Disorder b 148 (18) 104 (23) 44 (12) <0.001
Mood Disorder with Psychotic Features b (N = 827) 158 (19) 96 (22) 62 (16) 0.060
Psychotic Disorder b 365 (44) 174 (39) 191 (50) 0.001
Any substance use (N = 806) 535 (66) 301 (69) 234 (63) 0.067
Alcohol use 367 (44) 204 (46) 163 (43) 0.446
Opioid c use (N = 818) 89 (11) 57 (13) 32 (9) 0.047
Sedative use (N = 823) 13 (2) 8 (2) 5 (1) 0.580
Stimulant use d (N = 817) 234 (29) 141 (32) 93 (25) 0.025
THC use (N = 827) 290 (35) 163 (36) 127 (34) 0.388
Daily use of any substance (N = 819) 200 (24) 127 (29) 73 (19) 0.002
Polysubstance (≥3) use (N = 806) 118 (15) 77 (18) 41 (11) 0.008
Injection use (N = 818) 82 (10) 56 (13) 26 (7) 0.007

ap-value from chi2-Test; significant p-values in bold b at baseline. c includes heroin and prescription opioids d includes crack cocaine, powder cocaine, amphetamines, methamphetamine.