Figure 4.

AK4-promoted migration and invasion of the WM pair of cell lines. Shown are representative images (A) and quantification results (C) of the migration and invasion assay showing the influence of stable AK4 knockdown (with two different shRNAs) compared with shCtrl in WM-266-4 cells; (B) western blot showing the expression level of AK4 in WM-266-4 cells after stable knockdown of AK4; and (D,E) representative images (D) and quantification results (E) from the migration and invasion assay showing the influence of AK4 overexpression on the migratory and invasive capacities of WM-115 cells.