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. 2022 Jan 11;89(1):S29–S33. doi: 10.1097/QAI.0000000000002838

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FIGURE 1. — In addition to a direct proinflammatory effect, CMV potentiates microbial translocation of both bacterial (LPS) and fungal (BDG) products in ART-treated PLWH by inducing gut epithelial damage. Persistent inflammation and immune activation increase the risk of developing non-AIDS comorbidities and promote aging in ART-treated PLWH.