Table 2.
Summary of the studies concerning the role of IL-17F polymorphisms in cancer
| SNP | Cancer type | Total studies No. | No association No. | Association No. |
|---|---|---|---|---|
| rs763780 | Bladder | 3 | 2 | 1 |
| Blood (AML) | 3 | 2 | 1 | |
| Breast | 2 | 2 | – | |
| Cervix | 3 | 3 | – | |
| Colorectal | 7 | 4 | 3 | |
| Gastric | 10 | 7 | 3 | |
| Oral | 2 | 2 | – | |
| Larynx | 1 | 1 | – | |
| Liver (HBV-HCC) | 1 | 1 | – | |
| Lung | 2 | 1 | 1 | |
| Lymphoma | 1 | – | 1 | |
| Pancreas | 1 | 1 | ||
| Skin (BCC) | 1 | 1 | – | |
| rs9382084 | Breast | 1 | 1 | – |
| Cervix | 1 | 1 | – | |
| Gastric | 1 | – | 1 | |
| rs12203582 | Breast | 1 | 1 | – |
| Gastric | 1 | 1 | – | |
| Lung | 1 | – | 1 | |
| rs1266828 | Breast | 1 | 1 | – |
| Cervix | 1 | 1 | – | |
| Lung | 1 | 1 | – | |
| rs2397084 | Oral | 2 | 1 | 1 |
| Lung | 1 | 1 | – | |
| rs7771511 | Breast | 1 | 1 | – |
| rs641701, | Colorectal | 1 | – | 1 |
| rs9463772 | Colorectal | 1 | – | 1 |
Abbrevations: AML = acute myeloid leukemia, BCC = basal cell carcinoma, HBV-HCC = hepatitis B virus-related hepatocellular carcinoma