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. 2022 Jan 11;7(1):e01169-21. doi: 10.1128/msystems.01169-21

FIG 5.

FIG 5

Features of the main STs associated with CP-Ec isolates in France. At the top of the figure, for each ST, the phylogroup, the total number of isolates, and the number of isolates associated with urinary tract infections are indicated. Intermediate (Inter) and minor ST indicate ST represented by four to six isolates and one to three isolates, respectively. (A) Proportion of the isolates according to the carbapenemase allele in each ST. (B) Box plot representation of the ARGs content according to the ST. (C) Proportion of isolates according to the number of mutations in QRDR. (D) Proportion of isolates with a specific PBP3 allele. PBP3 characterized by a YRIP, YRIK, or YRIN insertion between positions 333 and 334, the YRIN insertion is generally associated with a A413V mutation (YRIN-L) and less frequently also with a E349K mutation (YRIN-K-L) (10). (E) Proportion of isolates carrying specific mutations in ompC: R195L, G138D or acquisition of an ST38-like ompC allele by recombination (10).