Table 3. SMs as human metabolites.
Name |
Role in induced cell reprogramming
(inducer/enhancer) |
Chemical class |
5'-Azacytidine (5'-azaC) | Enhancer | Nucleotides and nucleotide derivatives |
5'-Aza-2'-deoxycytidine | Enhancer | Nucleotides and nucleotide derivatives |
7-hydroxyflavone | Enhancer | Flavonoids |
90-D3 (Vitamin D3) | Enhancer | Steroids and steroid derivatives |
Apigenin | Enhancer | Flavonoids |
Caffeic acid | Putative enhancer or inducer | Cinnamic acids and derivatives |
Chlorogenic acid | Putative enhancer or inducer | Fatty acids and derivatives |
Curcumin | Enhancer | Diarylheptanoids |
Dasatinib | Inducer | Benzene and derivatives |
Dexamethasone | Enhancer | Steroids and steroid derivatives |
EGCG | Enhancer | Flavonoids |
Fisetin | Enhancer | Flavonoids |
Forskolin | Inducer | Benzofurans |
Fru-2,6-P2 | Enhancer | Organooxygen compounds |
Luteolin | Enhancer | Flavonoids |
N-acetyl-cysteine | Enhancer | Amino acids and derivatives |
Sodium Butyrate (NaB) | Inducer and enhancer | Fatty acids and derivatives |
Prostaglandin E2 | Enhancer | Fatty acids and derivatives |
Quercetin | Enhancer | Flavonoids |
Rapamycin | Enhancer | Macrolide lactams |
Resveratrol | Enhancer | Stilbenes |
Retinoic acid | Enhancer | Prenol lipids |
SAHA | Enhancer | Benzene and derivatives |
Spermidine | Enhancer | Organonitrogen compounds |
Valproic acid | Inducer | Fatty acids and derivatives |
Vitamin A (Retinol acetate) | Enhancer | Prenol lipids |
Vitamin C (Ascorbic acid; Ascorbate) | Enhancer | Dihydrofurans |
Zolpidem | Enhancer | Azoles |