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. 2021 Dec 27;15:807170. doi: 10.3389/fncel.2021.807170

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Copyright © 2021 Ahmed, Travis, Díaz-Bahamonde, Porter, Henry, Mykins, Ravipati, Booker, Ju, Ding, Ramesh, Pickrell, Wang, LaConte, Howell, Yuan and Morton.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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No effects of germ-free conditions on oligodendrogenesis within the subventricular zone at P16. (A) Gross anatomical map to demarcate region of interest (B). (B) Low magnification image of the SVZ, immunolabeled with Olig2 and Ki67, corresponding to inset (in A). (C) Higher magnification image of inset (in B). Quantification of the number of oligodendrocytes (D), proliferating cells (E), and proliferating oligodendrocytes (F). LV, lateral ventricle; C, control; GF, germ-free. Data not significant by unpaired student’s t test. Data expressed as mean ± SEM, n = 3–4 animals/group.