Table 4.
Comparison in different parameters in various studies using intralesional injections for treatment of post herpetic neuralgia
Name of study | Combination used | Maximum patients in age group/mean age in years | Sex | Commonest dermatome | duration of PHN in maximum patients (in months) | Duration >2 years | Mean VAS at baseline | Response rate |
---|---|---|---|---|---|---|---|---|
Bhargava et al.[4] | L: B: D: 3:2:0.02 freq 6 weeks | 60–80 (48%) | - | Thoracic (57%) | 0–6 (47%) | 12% | 85%% | |
Puri et al.[5] | L, B, D Concentration not mentioned, 6 weekly | 41–50 (33.3%) | M>F | Lumbo-sacral (60%) | 6–12 (40%) | 10% | 90% | |
Amjad et al.[6] | T: L: W: 1:5:44, 2 weekly | 61.06 | M>F | 83.3% | ||||
Ni et al.[7] | T2:L2::1:1 3 weekly | 65.86 | F>M | Thoracic 62% | Response better than 2% L | |||
Asim et al.[18] | T: W::3:7 | 45.93 | M>F | Thoracic 20.68% | 6.93 | |||
Khallid et al.[19] | 6 weekly | 60.2% | ||||||
Epstein et al.[20] | T only 2 weekly | 62.5% | ||||||
Our study | L: B: D::6:5:1 | 63.33±9.53 years | M>F | Thoracic (49%) | 0–6 (50%) | 7.730±1.622 | 50% excellent, 25% good response |
L (Lignocaine 2%), B (Bupivacaine 5%), D (Dexamethasone 4 mg/mL), T (Triamcinolone 40 mg/mL), T2 (triamcinolone 10 mg/mL), L2 (lignocaine 0.5%)