Figure 4.

(A) Expression of irisin in the serum. (B) Expression of irisin in the uterine tissue. (C) Effect of irisin on pAMPK expression in the uterus. Lane 1: sham group; Lane 2: sham+irisin (10 μg/kg, IV) group; Lane 3: LPS group; Lane 4-6: LPS + irisin (0.1, 1, 10 μg/kg, IV)-treated groups; Lane 7: LPS + irisin (10 μg/kg, IV) + compound C group. (D) Effect of irisin on NF-κBp65 expression in the uterus. Values were the mean ± SEM (n=6 per group). *** P<0.001 vs the sham group; #P<0.05, ## P<0.01, and ### P<0.001 vs LPS group; $P<0.05 and $$P<0.01 vs LPS + irisin (10 μg/kg, IV) group