Table 2.
Capsular Density and Collagen Fiber Alignment
Control Week 3 |
Fat Graft Week 3 |
Control Week 12 |
Fat Graft Week 12 |
Significance | AUC | |
---|---|---|---|---|---|---|
Capsular density | 3 (1, 3) | 1 (1) | 3 (1, 3) | 1 (1) | S† | 0.82 |
Collagen fiber alignment | 2 (2) | 1 (1) | 3 (3) | 2 (1, 2) | S‡ | 0.83 |
Data are expressed as the median, with the 25th percentile and the 75th percentile in parentheses.
Ordinal data (0 = Histology within normal limits; 1 = minimal alteration; 2 = mild alteration; 3 = moderate alteration; 4 = marked alteration) are expressed as the median, with the 25th percentile and the 75th percentile in parentheses; independent variables for each analysis were fat graft, time, and % collagen (% collagen was not an independent variable for the % collagen analysis). Control, week 3, n = 10; fat graft group, week 3, n = 7; control, week 12, n = 10; fat graft group, week 12, n = 9.
†No significant effect of % collagen; those with a fat graft were 69 times less likely to have a higher capsular density score than those without a fat graft (P = 0.001); those at 12 weeks were 12.9 times more likely to have a higher capsular density score than those at 3 weeks (P = 0.020).
‡No significant effect of % collagen; those with a fat graft were 67 times less likely to have a higher fiber alignment score than those without a fat graft (P < 0.001); those at 12 weeks were 15 times more likely to have a higher fiber alignment score than those at 3 weeks (P = 0.001).
AUC: Area under the curve; S: Significant finding (P < 0.05).