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. 2021 Mar 15;77(1):188–196. doi: 10.1093/gerona/glab080

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Figure 2. — Comparison of biomarkers of proinflammation and immunosuppression between older and young sepsis patients. Proinflammation: (A) interleukin-6 (IL-6), (B) IL-8, (C) monocyte chemoattractant protein 1 (MCP-1), and (D) C-reactive protein (CRP) and (E) absolute neutrophil count (ANC). Immunosuppression: (F) soluble programmed death ligand 1 (sPDL-1), (G) IL-10, and (H) absolute lymphocyte count (ALC) biomarkers. Perforated line represents biomarker levels in matched control subjects. Shaded area represents published normal reference ranges. Data presented as median (25% and 75%) with statistical significance set at p <.05 and asterisk represents statistical significance of the older (vs young) and older chronic critical illness (CCI) (vs older rapidly recover [RAP]) cohorts.