Table 2.
Estimated β Coefficients From the CHARGE‐AF and the Re‐CHARGE‐AF Models
| CHARGE‐AF Estimated β (SE) 12 | CHARGE‐AF HR (95% CI) 12 | Re‐CHARGE‐AF Estimated β (SE) | Re‐CHARGE‐AF HR (95% CI) | |
|---|---|---|---|---|
| Age (5 y) | 0.508 (0.022) | 1.66 (1.59–1.74) | 0.286 (0.065) | 1.33 (1.17–1.51) |
| Race (White)* | 0.465 (0.093) | 1.59 (1.33–1.91) | −0.686 (0.309) | 0.50 (0.27–0.92) |
| Height (10 cm) | 0.248 (0.036) | 1.28 (1.19–1.38) | −0.133 (0.128) | 0.88 (0.68–1.13) |
| Weight (15 kg) | 0.115 (0.033) | 1.12 (1.05–1.20) | 0.421 (0.117) | 1.52 (1.21–1.92) |
| Systolic BP (20 mm Hg) | 0.197 (0.033) | 1.22 (1.14–1.30) | 0.023 (0.114) | 1.02 (0.82–1.28) |
| Diastolic BP (10 mm Hg) | −0.101 (0.032) | 0.90 (0.85–0.96) | −0.116 (0.121) | 0.89 (0.70–1.13) |
| Smoking (current) | 0.359 (0.091) | 1.43 (1.20–1.71) | −0.517 (0.387) | 0.60 (0.28–1.27) |
| Antihypertensive medication use | 0.349 (0.063) | 1.42 (1.25–1.60) | 0.004 (0.273) | 1.00 (0.59–1.72) |
| Diabetes (yes) | 0.237 (0.073) | 1.27 (1.10–1.46) | −0.488 (0.291) | 0.61 (0.35–1.09) |
| Heart failure (yes) | 0.701 (0.106) | 2.02 (1.64–2.48) | 0.627 (0.379) | 1.87 (0.89–3.93) |
| Myocardial infarction (yes) | 0.496 (0.089) | 1.64 (1.38–1.96) | 0.282 (0.396) | 1.33 (0.61–2.88) |
BP indicates blood pressure; and HR, hazard ratio.
*
For the Cohorts for Heart and Aging Research in Genomic Epidemiology for Atrial Fibrillation (CHARGE‐AF) model, the race coefficient corresponds to White persons compared with Black persons. For the fully refitted CHARGE‐AF (Re‐CHARGE‐AF) model, the race coefficient corresponds to non‐Hispanic White persons compared with persons from all other race/ethnic groups.