Skip to main content
. 2021 Oct 6;10(20):e020974. doi: 10.1161/JAHA.121.020974

Table 5.

Univariable Cox Regression Analysis for Stent Thrombosis Within 12 Months After Discontinuation of Dual Antiplatelet Therapy in 60 227 Patients With Myocardial Infarction Treated With PCI Who Did Not Continue With Dual Antiplatelet Therapy Beyond 12 Months From Their Index Myocardial Infarction

HR (95% CI) P value
Age (for each 10 y increase)* 0.9 (0.8–1.1) 0.274
Age ≥75 y 0.8 (0.5–1.3) 0.315
Body weight <60 kg 0.5 (0.2–1.7) 0.298
Women 0.7 (0.4–1.1) 0.111
ST‐segment–elevation myocardial infarction 1.1 (0.7–1.6) 0.722
Hypertension 0.9 (0.6–1.3) 0.485
Hyperlipidemia 2.0 (1.4–3.0) <0.001
Current smoking 1.1 (0.7–1.8) 0.574
Diabetes 1.1 (0.6–1.8) 0.754
Diabetes with insulin therapy 1.2 (0.6–2.5) 0.634
Peripheral artery disease 2.6 (1.2–5.7) 0.013
Heart failure 1.3 (0.5–3.5) 0.638
Chronic obstructive pulmonary disease 0.6 (0.2–1.8) 0.577
Cancer within 3 y 0.5 (0.1–3.5) 0.471
Previous myocardial infarction 2.1 (1.4–3.4) 0.001
Previous PCI 2.9 (1.8–4.6) <0.001
Previous coronary artery bypass graft 3.5 (2.0–6.2) <0.001
Previous stroke 1.6 (0.7–3.5) 0.228
Previous bleeding 0.8 (0.3–2.6) 0.723
Hemoglobin (for each 10 g/L increase) 0.9 (0.5–1.5) 0.578
Anemia 1.2 (0.7–2.0) 0.544
Creatinine clearance (for each 10 mL/min per 1.73 m2 increase) § 1.0 (0.9–1.1) 0.986
Kidney dysfunction 1.5 (0.9–2.4) 0.101
Bifurcation lesion 0.8 (0.4–1.5) 0.455
Complex lesion 2.0 (1.3–3.1) 0.001
Drug–eluting stent 0.4 (0.3–0.6) <0.001
Stent length (for each mm increase) 1.0 (1.0–1.0) 0.297

HR indicates hazard ratio; and PCI, percutaneous coronary intervention.

*

Age was truncated below 50 years.

Hemoglobin was truncated above 120 g/L and below 100 g/L.

Anemia is hemoglobin <120 g/L for women and <130 g/L for men.

§

Creatinine clearance was truncated above 100 mL/min per 1.73 m2.

Kidney dysfunction is creatinine clearance <60 mL/min per 1.73 m2.