Table 2.
Overview of Cardiovascular Events
| All patients (n=920) | Low‐risk CoA* (n=376) | High‐risk CoA † (n=544) | ||||
|---|---|---|---|---|---|---|
| No. of cases | Incidence per 1000 patient‐y | No. of cases | Incidence per 1000 patient‐y | No. of cases | Incidence per 1000 patient‐y | |
| CAD | 14 | 1.6 | 4 | 1.3 | 10 | 1.9 |
| Myocardial infarction | 6 | 0.7 | 1 | 0.3 | 5 | 0.9 |
| Coronary revascularization | 6 | 0.7 | 2 | 0.6 | 4 | 0.7 |
| Stable angina, medically treated | 2 | 0.2 | 1 | 0.3 | 1 | 0.2 |
| Stroke/TIA | 34 | 4.0 | 9 | 2.8 | 25 | 4.7 |
| Ischemic stroke | 18 | 2.1 | 5 | 1.6 | 13 | 2.4 |
| Hemorrhagic stroke, intracerebral | 1 | 0.1 | 1 | 0.3 | 0 | 0 |
| Hemorrhagic stroke, subarachnoidal | 1 | 0.1 | 0 | 0 | 1 | 0.2 |
| TIA | 14 | 1.6 | 3 | 0.9 | 11 | 2.1 |
| Aortic complication | 84 | 9.9 | 16 | 5.1 | 68 | 12.7 |
| Aneurysm | 77 | 9.0 | 15 | 4.7 | 62 | 11.6 |
| Dissection | 7 | 0.8 | 1 | 0.3 | 6 | 1.1 |
| Arrhythmia | 84 | 9.9 | 22 | 6.9 | 62 | 11.6 |
| Supraventricular arrhythmia | 58 | 6.8 | 15 | 4.7 | 43 | 8.0 |
| Ventricular arrhythmia | 18 | 2.1 | 4 | 1.3 | 14 | 2.6 |
| Conduction disturbance | 8 | 0.9 | 3 | 0.9 | 5 | 0.9 |
| Heart failure hospitalization | 15 | 1.8 | 6 | 1.9 | 9 | 1.7 |
| Endocarditis | 15 | 1.8 | 2 | 0.6 | 13 | 2.4 |
| Cardiovascular death | 24 | 2.8 | 8 | 2.5 | 16 | 3.0 |
| Total cardiovascular events | 270 | 31.7 | 67 | 21.1 | 203 | 38.0 |
| No. of individual patients with cardiovascular event | 191 | NA | 48 | NA | 143 | NA |
CAD indicates coronary artery disease; NA, not applicable; and TIA, transient ischemic attack.
*
Includes patients with isolated coarctation of the aorta (CoA) or patients with any of the following associated lesions: closed or small ventricular septal defect, atrial septal defect, patent foramen ovale, or patent ductus arteriosus.
†
Includes patients with a bicuspid aortic valve, left‐sided mechanical heart valve, and/or Turner syndrome.