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. 2022 Jan 11;17(1):e0262544. doi: 10.1371/journal.pone.0262544

Fig 4. Mitochondrial Complex I activity in whole blood following chemotherapy administration.

Fig 4

Complex I activity is normalized to Complex I quantity. (A) Complex I activity in animals administered with four injections of 2 mg/kg paclitaxel or an equal volume of vehicle solution. Day 7: n = 6 per group; peak pain: n = 7 per group. (B) Complex I activity in animals administered with four injections of 2 mg/kg oxaliplatin or an equal volume of vehicle solution. Day 7 and peak pain: n = 5 per group. (C) Complex I activity in animals administered with four injections of 0.2 mg/kg bortezomib or an equal volume of vehicle solution. Day 4 and peak pain: n = 6 per group. Data are expressed as mean ± SEM. Unpaired two-tailed t-tests.