Table V.
Flap Number and Flap to Capsule Fraction Difference for Carrier-Based Budesonide Formulations and Carrier-Free Rifampicin Formulations Characterized from ACGcaps™ HI, Embocaps® VG, Vcaps®, and Quali-V® I Capsules at 2-kPa and 4-kPa Drop Conditions. Flap Number is Defined as the Number of Attached Flaps on the Capsule Pieces After NGI. Flap to Capsule Fraction is Defined as the Portion of Capsule Pieces with Attached Flaps Among All Actuated Capsule Pieces
| Capsules types | Embocaps® VG | Vcaps® | Quali-V® I | ACGCAPS™ HI | |||||
|---|---|---|---|---|---|---|---|---|---|
| 2 kPa | 4 kPa | 2 kPa | 4 kPa | 2 kPa | 4 kPa | 2 kPa | 4 kPa | ||
| Total flap number after NGI | Carrier-based | 21 | 24 | 15 | 11 | 33 | 25 | 28 | 28 |
| Carrier-free | 6 | 3 | 2 | 2 | 7 | 3 | 5 | 3 | |
| Flap to piercing fraction after NGI (%) | Carrier-based | 52.5 | 60 | 37.5 | 27.5 | 82.5 | 62.5 | 70 | 70 |
| Carrier-free | 75 | 37.5 | 25 | 25 | 87.5 | 37.5 | 62.5 | 37.5 | |