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Design and proposed mechanism of PNP-D-mAb. (A) The structure of the cholesterol-modified CPP. (B) Schematic illustration of the nanoparticle formation process including peptide self-assembling, drug loading, and mAb modification. (C) The proposed mechanism of PNP-D-mAb in CAFs targeting and drug penetration. Adapted with permission from ref 97. copyright (2015) Wiley.
