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. Author manuscript; available in PMC: 2022 Jan 11.
Published in final edited form as: Pediatr Blood Cancer. 2020 Jan 23;67(5):e28098. doi: 10.1002/pbc.28098
PD < 50% tumor regression throughout study and > 25% tumor growth at the end of the study.
PD1 PD and the mouse’s time to event ≤ 200% the Kaplan-Meier (KM) median time to event in the control group.
PD2 PD and the mouse’s time to event > 200% of the KM median time to event in the control group.
SD < 50% tumor regression throughout study and ≤25% tumor growth at the end of the study.
PR ≥50% tumor regression at any point during study, but measurable tumor throughout the study period.
CR Disappearance of measurable tumor mass during the study period.
MCR No measurable tumor mass for at least three consecutive weekly readings at any time after treatment has been completed.