PD |
< 50% tumor regression throughout study and > 25% tumor growth at the end of the study. |
PD1 |
PD and the mouse’s time to event ≤ 200% the Kaplan-Meier (KM) median time to event in the control group. |
PD2 |
PD and the mouse’s time to event > 200% of the KM median time to event in the control group. |
SD |
< 50% tumor regression throughout study and ≤25% tumor growth at the end of the study. |
PR |
≥50% tumor regression at any point during study, but measurable tumor throughout the study period. |
CR |
Disappearance of measurable tumor mass during the study period. |
MCR |
No measurable tumor mass for at least three consecutive weekly readings at any time after treatment has been completed. |