Table 2.
Treatment Outcomes of Intramuscular Corticosteroid Therapy in Participants with Alopecia Areata
| Treatment Outcomes | N = 101 |
|---|---|
| Treatment failure (<10% regrowth) | |
| ● Incidence, n (%) | 3 (2.9) |
| Initial hair regrowth (25% regrowth) | |
| ● Cumulative incidence, n (%) | 86 (85.1) |
| ● Incidence rate, person-year (CI) | 64.0 (51.9–79.3) |
| ● Median time to achieve endpoint, month (CI) | 0.9 (0.8–1.2) |
| ● Median cumulative dose to achieve endpoint, mg | 100 |
| ● Cumulative dose to achieve endpoint, mg, median (IQR) | 80 (20–160) |
| Significant hair regrowth (75% regrowth) | |
| ● Cumulative incidence, n (%) | 81 (80.2) |
| ● Incidence rate, person-year (CI) | 17.0 (13.6–21.7) |
| ● Median time to achieve endpoint, month (CI) | 3.4 (2.9–4.4) |
| ● Median cumulative dose to achieve endpoint, mg | 200 |
| ● Cumulative dose to achieve endpoint, mg, median (IQR) | 120 (40–200) |
| Complete hair regrowth (100% regrowth) | |
| ● Cumulative incidence, n (%) | 49 (48.5) |
| ● Incidence rate, person-year (CI) | 8.0 (6.2–10.9) |
| ● Median time to achieve endpoint, month (CI) | 6.1 (5.1–8.1) |
| ● Cumulative dose to achieve endpoint, mg, median (IQR) | 160 (60–240) |
| Relapse | |
| ● Cumulative incidence, n (%) | 48 (47.5) |
| ● Incidence rate, person-year (CI) | 5.5 (4.2–7.3) |
| ● Median time to relapse, month (CI) | 11.3 (8.6–15.4) |
Abbreviations: CI, confidence interval; IQR, interquartile range.