Table 4.
Univariate and Multivariable Analyses for the Factor Associated with Relapse After Intramuscular Corticosteroid Therapy in Patients with Alopecia Areata
| Variables | HR (95% CI) | P-value | Adjusted HR (95% CI) | P-value |
|---|---|---|---|---|
| Female | 1.15 (0.64–1.69) | 0.536 | ||
| Age at AA onset | 1.01 (0.99–1.06) | 0.104 | ||
| Age group at AA onset | ||||
| ● ≤40 years | Reference | |||
| ● >40 years | 1.55 (0.78–2.56) | 0.151 | ||
| Duration of disease >6 months | 3.12 (1.36–4.94) | 0.016* | 4.02 (1.52–4.66) | 0.005* |
| AA subtype | ||||
| ● Patch AA | Reference | |||
| ● Multiple AA | 0.94 (0.66–2.67) | 0.723 | ||
| ● Diffuse AA | 0.85 (0.39–3.62) | 0.264 | ||
| ● AT | 3.12 (0.79–5.64) | 0.459 | ||
| ● AU | 2.92 (0.59–3.95) | 0.644 | ||
| ● Ophiasis | 1.49 (0.08–3.12) | 0.814 | ||
| Severity of AA (SALT score) | ||||
| ● 0–25% | Reference | |||
| ● 26–50% | 0.91 (0.72–2.19) | 0.135 | ||
| ● 51–75% | 1.14 (0.51–2.67) | 0.718 | ||
| ● 76–100% | 0.69 (0.29–1.89) | 0.653 | ||
| Body hair involvement | 1.05 (0.29–3.18) | 0.425 | ||
| Nail involvement | 2.78 (0.98–4.09) | 0.812 | ||
| Atopy | 1.34 (0.63–3.89) | 0.291 | ||
| Autoimmune thyroid diseases | 2.39 (1.42–5.14) | 0.041* | 2.71 (0.82–4.65) | 0.069 |
| Family history of AA | 1.76 (0.87–2.88) | 0.635 |
Note: *Statistically significant.
Abbreviations: AA, alopecia areata; AT, alopecia totalis; AU, alopecia universalis; CI, confidence interval; HR, hazard ratio; SALT, Severity of Alopecia Tool.