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. 2022 Jan 7;17:73–89. doi: 10.2147/IJN.S346044

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© 2022 Zhao et al.

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Physicochemical characterization of R837@HM-NPs. Size distributions (A–C) from dynamic light scattering analysis of MSN, R837@MSN and R837@HM-NPs. (D) Evidence for the coverage of hybrid membrane coated on the surface of MSN by confocal microscopy. (E) Size changes of R837@HM-NPs over seven successive days in PBS. (F) Zeta potential changes of R837@HM-NPs in seven successive days in PBS. (G) In vitro release profiles of R837 from R837@MSN and R837@HM-NPs in PBS (at pH 5.0 and pH 7.4). (H) Cell viability of BMDCs incubated with PBS, MSN and HM-NPs at different concentrations measured at 48 h.