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. 2022 Jan 7;17:73–89. doi: 10.2147/IJN.S346044

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© 2022 Zhao et al.

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The immune stimulatory effect of R837@HM-NPs on BMDCs in vitro. (A) Representative flow cytometry data to show BMDCs maturation induced by different treatments in vitro. (B) Representative statistical data to show BMDCs maturation induced by different treatments in vitro. ELISA results of IL-6 (C), IL-12p40 (D), and TNF-α (E) secretion from BMDCs after R837@HM-NPs treatment. (F) Flow cytometric analyses of the expression of CD4 and CD8, the markers for T cell activation, after in vitro incubation of T cells with PBS, R837, R837@MSN, HM-NPs, and R837@HM-NPs for 24 h. *P < 0.05, **P < 0.01.