TABLE 1.
Treatment detailsa
| Treatment group | Active ingredient | Route | No. of animals treated | Total grams used | Treatment days per regimen | Used daily doses | Animal treatment days (per 1000 days at risk) |
|---|---|---|---|---|---|---|---|
| Minimal | Penicillin G procaine | Injection | 4 | 2.1 | 3 | 12 | |
| Lincomycin | Injection | 1 | 0.5 | 3 | 3 | ||
| Total | 2.6 | 15 | 2.8 | ||||
| Moderate | Penicillin G procaine | Injection | 3 | 1.5 | 3 | 9 | |
| Ceftiofur | Injection | 7 | 0.9 | 7 | 49 | ||
| Tilmicosin | Water | 36 | 112.5 | 5 | 180 | ||
| Total | 114.9 | 238 | 44.1 | ||||
| Intensive | Penicillin G procaine | Injection | 1 | 1.1 | 3 | 3 | |
| Ceftiofur | Injection | 36b | 4.4 | 7 | 259 | ||
| Tilmicosin | Water | 36 | 112.5 | 5 | 180 | ||
| Chlortetracycline/ tiamulin | Feed | 36 | 460/37.5 | 14 | 504 | ||
| Total | 615.5 | 946 | 181.5 |
a
Used daily doses, total grams (g) used, and animal treatment days per 1000 days at risk were calculated based on actual usage during study. Penicillin G procaine and lincomycin were administered daily for 3 days per treatment regimen; ceftiofur was administered once per treatment regimen.
b
Note: 37 individual treatments with ceftiofur were administered to the Intensive treatment group (n = 36) as all individuals were treated at 7 days post-PRRSV challenge and one was later also treated individually (11 days post-PRRSV challenge).