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. 2022 Jan 11;88(1):e01583-21. doi: 10.1128/AEM.01583-21

TABLE 2.

Summary of MICs of antimicrobials determined in duplicate by the microdilution method for B. mayonis sp. nov. (Bm) and B. savannae sp. nov. (Bs)

Antimicrobial substance MIC (mg/liter)
Resistance breakpoint (mg/liter) if available Bm
BDU6T
Bm
BDU8
Bs
MSMB266T
Bs
MSMB852
Bs
BDU18
Bs
BDU19
Amoxicillin/clavulanic acida ≥32/16 (40) 8/4 ≤4/2 8/4 8/4 8/4 8/4
Azithromycin >64 >64 >64 >64 >64 >64
Carbenicillin 128 64 64 32 64 64
Ceftazidime ≥32 (40) ≤4 ≤4 ≤4 ≤4 ≤4 ≤4
Ceftazidime-avibactamb 4/4 1/4 ≤0.5/4 ≤0.5/4 ≤0.5/4 ≤0.5/4
Chloramphenicol ≥32 (41) 32 16 8 16 8 16
Ciprofloxacin 2 ≤0.5 ≤0.5 ≤0.5 1 1
Doripenem ≤0.5 ≤0.5 ≤0.5 ≤0.5 ≤0.5 ≤0.5
Doxycycline ≥16 (40) ≤1 ≤1 ≤1 ≤1 ≤1 ≤1
Gentamicin 32 >64 32 32 64 64
Imipenem ≥16 (40) ≤1 ≤1 ≤1 ≤1 ≤1 ≤1
Kanamycin 16 32 16 16 16 32
Meropenem ≥16 (41) ≤1 ≤1 ≤1 ≤1 ≤1 ≤1
Piperacillin ≤8 ≤8 ≤8 ≤8 ≤8 ≤8
Piperacillin-tazobactam ≤8/4 ≤8/4 ≤8/4 ≤8/4 ≤8/4 ≤8/4
Polymyxin B 512 >2048 512 >2048 >2048 >2048
Sulfamethoxazole >512 256 >512 >512 >512 >512
Tigecycline 1 0.5 2 1 1 1
Trimethoprim 4 4 2 ≤1 4 2
Trimethoprim/sulfamethoxazole ≥4/76 (40) 2/38 ≤1/19 ≤1/19 ≤1/19 ≤1/19 ≤1/19
a

For amoxicillin-clavulanic acid, clavulanic acid was maintained at 4 μg/ml in all wells.

b

For ceftazidime-avibactam, avibactam was maintained at 4 μg/ml in all wells.