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. 2022 Jan 4;2022:1458143. doi: 10.1155/2022/1458143

Table 1.

Drugs associated with ferroptosis.

Drug Target Application Reference
Cisplatin GSH Ovarian cancer, pancreatic cancer [124, 125]
Neratinib Iron metabolism Breast cancer [127]
Lapatinib Iron metabolism Breast cancer [129]
Sorafenib System Xc- Renal cell carcinoma, hepatocellular carcinoma [130]
Sulfasalazine System Xc- Immune diseases [131]
Auranofin Thioredoxin reductase Rheumatoid arthritis [132]