Figure 3.
Effect of H2S on the cognitive impairment of ROT-induced PD rats in the NOR test. After pretreatment with NaHS (30 and 100 μmol/kg, i.p.) for 1 w, SD rats were injected with ROT (2 mg/kg, s.c.) for 5 w and NaHS for 3 w simultaneously. Rats were subjected to the NOR test. The total time in the training period (a) and the recognition index (b) as well as total time (c) in the test period over the course of 5 min were assessed. Values are presented as the mean ± S.E.M. (n = 9–15). ∗∗P < 0.01 vs. control group; #P < 0.05 vs. ROT exposure alone group.