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. 2022 Jan 4;2022:2792348. doi: 10.1155/2022/2792348

Figure 9.

Figure 9

Effect of 2-DG on H2S-ameliorated cognitive impairment of ROT-induced PD rats in the NOR test. After pretreatment with NaHS (100 μmol/kg, i.p.) for 1 w, SD rats were injected with ROT (2 mg/kg, s.c.) for 5 w. In the 3rd week of ROT injection, rats were cotreated with NaHS (100 μmol/kg, i.p.) and 2-DG (3 μg/w, i.c.v.) for 3 w simultaneously. All rats were subjected to the NOR test. The total time in the training period (a) and recognition index (b) as well as the total time (c) in the test period over the course of 5 min were recorded. Values are presented as the mean ± S.E.M. (n = 9–15). ∗∗P < 0.01 vs. control group; #P < 0.05 vs. ROT treatment alone group; &P < 0.05 vs. ROT and NaHS cotreatment groups.