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. 2022 Jan 4;2022:5914541. doi: 10.1155/2022/5914541

Figure 4.

Figure 4

PAX2 is highly expressed in serum of HCC patients. (a) Volcano plots for the differentially expressed mRNAs in the GSE138178 dataset; (b) a heatmap of the top 50 differentially expressed mRNAs in the GSE138178 dataset; (c–g) the staining intensities of PAX2, CCND1, MYC, NEDD4, and CXCL5 in normal liver tissues and HCC tissues were determined through the Human Protein Atlas website (https://www.proteinatlas.org/); (h) PAX2, CCND1, MYC, NEDD4, and CXCL5 expressions in the serum of 31 healthy subjects and 59 HCC patients was detected using RT-qPCR. Data in panel H were analyzed utilizing the unpaired t-test.  ∗∗p < 0.01;  ∗∗∗p < 0.001.