Table 1.
Features of 15 patients diagnosed with DLBCL with fresh and frozen samples.
| Item | GCB group | ABC group | p value |
|---|---|---|---|
| N | 5 | 10 | – |
|
| |||
| Age (years) | |||
| <50 | 2 (2/5, 40) | 5 (5/10, 50) | 1.000 |
| >50 | 3 (3/5, 60) | 5 (5/10, 50) | |
|
| |||
| Gender, n (%) | |||
| Male | 3 (3/5, 60) | 8 (8/10, 80) | 0.560 |
| Female | 2 (2/5, 40) | 2 (2/10, 20) | |
|
| |||
| Primary localization, n (%) | |||
| Intranodal | 4 (5/5, 80) | 6 (6/10, 60) | 0.600 |
| Extranodal | 1 (1/5, 20) | 4 (4/10, 40) | |
|
| |||
| Laboratory parameter, mean ± SD (109/l) | |||
| Leukocytes | 10.45 ± 4.01 | 5.91 ± 3.33 | 0.036∗ |
| Hemoglobin | 121.80 ± 22.20 | 103.90 ± 26.47 | 0.218 |
| Thrombocyte | 264.80 ± 110.25 | 119.60 ± 89.30 | 0.016∗ |
| LDH increased, n (%) | 2 (2/5, 40) | 4 (4/10, 40) | 1.000 |
| B-symptoms, n (%) | 1 (1/5, 20) | 4 (4/10, 40) | 0.007∗ |
|
| |||
| Ann Arbor stage, n (%) | |||
| I∼II (early stage) | 3 (3/5, 60) | 2 (2/10,20) | 0.251 |
| III∼IV (late stage) | 2 (2/5, 40) | 8 (8/10, 80) | |
| Bone marrow involvement, n (%) | 0 (0) | 2 (2/10, 20) | 0.007∗ |
| hsa-miRNA-28-5p, mean ± SD | 0.502 ± 0.274 | 0.699 ± 0.382 | 0.566 |
| YWHAZ, mean ± SD | 1.252 ± 0.407 | 2.331 ± 0.811 | 0.004∗ |
| Overall survival, n (%) | 3 (3/5, 60) | 8 (8/10, 80) | 0.353 |