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. 2022 Jan 4;2022:3109165. doi: 10.1155/2022/3109165

Table 4.

Univariate analysis of overall survival by the Cox proportional hazards model.

Characteristics N HR 95% CI P value
Age <65 Y 87 REF 1.21–2.82 0.005
≥65 Y 243 1.84

Sex Male 198 REF 0.45–0.90 0.011
Female 132 0.64

Primary site Rectum 129 REF 0.91–1.81 0.149
Colon 201 1.29

Tumor size <5 cm 205 REF 0.69–1.35 0.83
5+ cm 125 0.96

T stage T0–T2 68 REF 0.90–2.14 0.138
T3–T4 262 1.39

N stage N0 185 REF 1.18–2.26 0.003
N1–N3 145 1.63

M stage M0 275 REF 1.52–3.30 <0.001
M1 55 2.24

Stage I-II 163 REF 1.19–2.30 0.003
III-IV 167 1.65

NLR Low 176 REF 1.41–2.73 <0.001
High 154 1.96

PLR Low 148 REF 1.21–2.40 0.002
High 182 1.70

CEA (ng/mL) Low 244 REF 1.46–2.89 <0.001
High 86 2.05

CEA + NLR Low 141 REF 1.67–3.42 <0.001
High 189 2.39

CEA + PLR Low 117 REF 1.36–2.90 <0.001
High 213 1.99

NLR + PLR Low 116 REF 1.44–3.09 <0.001
High 214 2.11

CEA + NLR + PLR Low 94 REF 1.65–3.99 <0.001
High 236 2.57

BMI Low 155 REF 0.26–0.52 <0.001
High 175 0.36