Table 1.
List of NAESS tables used by reviewers to define severity to cases.
| Name of NAESS scoring table | Serious adverse event | Adverse event |
|---|---|---|
| AEs category as defined by original RCT | 35 | 25 |
| Generic NAESS tablea | 9 | 12 |
| Infectious—Neonatal Culture Positive Sepsis | 5 | 0 |
| Neurological—Neonatal Intraventricular Hemorrhage (IVH) | 3 | 3 |
| Respiratory—Infantile Apnea | 2 | 3 |
| Infectious—Neonatal Culture Negative Sepsis | 2 | 1 |
| Neurological—Retinopathy of Prematurity (ROP) | 2 | 1 |
| Respiratory—Neonatal Respiratory Insufficiency | 2 | 1 |
| Gastro-intestinal—Neonatal Gastrointestinal Bleeding | 2 | 0 |
| Gastro-intestinal—Feeding Intolerance | 1 | 1 |
| Respiratory—Neonatal Pulmonary Hemorrhage | 1 | 1 |
| Cardiovascular—Neonatal Coagulation Disorder | 1 | 0 |
| Cardiovascular—Neonatal Edema | 1 | 0 |
| Cardiovascular—Neonatal Tachyarrhythmia | 1 | 0 |
| Gastro-intestinal—Neonatal Spontaneous Intestinal Perforation (SIP) | 1 | 0 |
| Gastro-intestinal— Necrotizing Enterocolitis (NEC) | 1 | 1 |
| Respiratory—Neonatal Pneumothorax | 1 | 0 |
| Cardiovascular—Neonatal Hypotension | 0 | 1 |
| Gastro-intestinal—Necrotizing Enterocolitis (NEC) | 0 | 1 |
aCases where the generic table was used included PDA, pneumonia, UTI, feeding intolerance, hepatic bleeding, conjunctivitis, inguinal hernia, anemia, thrombocytopenia, hyperbilirubinemia.
The AE-specific tables are listed in descending order by frequency of use.