TABLE 1.
Patient characteristics by timing of leiomyosarcoma diagnosis (N=79)
| Patient Characteristics | Diagnosed Preoperatively (N=46) | Diagnosed Postoperatively (N=33) | P Value |
|---|---|---|---|
| Age, years | .27 | ||
| 18–54 | 14 (50.0%) | 14 (50.0%) | |
| ≥55 | 32 (62.7%) | 19 (37.3%) | |
| Race/ethnicity | .31 | ||
| Non-Hispanic white | 29 (63.0%) | 17 (37.0%) | |
| Other/unknown | 17 (51.5%) | 16 (48.5%) | |
| Primary payer | .83 | ||
| Private insurance | 29 (59.2%) | 20 (40.8%) | |
| Other/unknown | 17 (56.7%) | 13 (43.3%) | |
| Cancer stage | .71 | ||
| Localized | 25 (54.3%) | 21 (45.7%) | |
| Regional | 11 (64.7%) | 6 (35.3%) | |
| Distant | 10 (62.5%) | 6 (37.5%) | |
| Tumor grade | .16 | ||
| 1–2 | 2 (100.0%) | 0 (0.0%) | |
| 3 | 11 (47.8%) | 12 (52.2%) | |
| 4 | 23 (69.7%) | 10 (30.3%) | |
| Unknown | 10 (47.6%) | 11 (52.4%) | |
| Tumor size (in centimeters),a mean±SD, median (interquartile range) | 8.6±4.6, 9 (6–11) | 11.2±5.0, 11 (8.5–14.5) | .04 |
| Presence of a diagnosis code for leiomyoma | .09 | ||
| Yes | 15 (46.9%) | 17 (53.1%) | |
| No | 31 (66.0%) | 16 (34.0%) | |
| Postmenopausal bleeding | .12 | ||
| Yes | 29 (65.9%) | 15 (34.1%) | |
| No | 17 (48.6%) | 18 (51.4%) | |
| Premenopausal menorrhagia or frequent menstruation | .33 | ||
| Yes | 6 (46.2%) | 7 (53.8%) | |
| No | 40 (60.6%) | 26 (39.4%) | |
| Diabetes | .73 | ||
| Yes | 6 (66.7%) | 3 (33.3%) | |
| No | 40 (57.1%) | 30 (42.9%) | |
| Hypertension | .09 | ||
| Yes | 18 (72.0%) | 7 (28.0%) | |
| No | 28 (51.9%) | 26 (48.1%) | |
| Obesity | 1.00 | ||
| Yes | 2 (66.7%) | 1 (33.3%) | |
| No | 44 (57.9%) | 32 (42.1%) | |
| Additional MRI/transvaginal ultrasound evaluation in 90-day preoperative periodb | .64 | ||
| Yes | 3 (75.0%) | 1 (25.0%) | |
| No | 43 (57.3%) | 32 (42.7%) | |
| Type of endometrial sampling | .007 | ||
| With hysteroscopy | 40 (66.7%) | 20 (33.3%) | |
| Without hysteroscopy | 6 (31.6%) | 13 (68.4%) |
MRI = Magnetic resonance imaging; SD = standard deviation.
a.
N=18 patients had missing data on tumor size.
b.
Limited to MRI/transvaginal ultrasound documented in hospital discharge records.