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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Nitric Oxide. 2021 Dec 4;119:9–18. doi: 10.1016/j.niox.2021.12.002

Figure 8: Effect of SODm on the TSE-induced increase in NO metabolism rate in Cygb-KD VSMCs.

Figure 8:

Cygb-siRNA pretreated (Cygb-KD) cells were either untreated (UT) or treated with 1% tobacco smoke extract (TSE), in the presence or absence of the SODm, for 48 hr and then harvested for measurement of NO metabolism, VNO, measured as in Figure 2. Cell density of 3.5 × 106 VSMCs per ml was used in all groups. Each value represents the mean of 4 independent experiments ± SEM. *: Denotes significant difference from the UT control cells at p < 0.001. #: Denotes significant difference from TSE-treated cells pre-incubated with SODm at p < 0.001.