Table 1.
Sample demographics.
| Variable | MDD n = 207 | HC n = 32 | p-Value |
|---|---|---|---|
| Age, years, mean (SD) | 38.9 (13.2) | 38.8 (15.1) | 0.988 |
| Sex, n (%) | 0.552 | ||
| Female | 140 (67.6) | 20 (62.5) | |
| Male | 67 (32.4) | 12 (37.5) | |
| Race, n (%) | 0.710 | ||
| White | 138 (66.7) | 30 (67.5) | |
| African American | 39 (18.8) | 8 (25.0) | |
| Other | 30 (14.5) | 4 (12.5) | |
| Ethnicity | 0.082 | ||
| Hispanic | 40 (19.3) | 2 (6.2) | |
| Non-Hispanic | 167 (80.7) | 30 (93.8) | |
| Site | 0.005 | ||
| Columbia | 63 (30.4) | 9 (28.1) | |
| Massachusetts General | 16 (7.7) | 9 (28.1) | |
| Michigan | 51 (24.6) | 7 (21.9) | |
| UTSW | 77 (37.2) | 7 (21.9) | |
| BMI, mean (SD), kg | 29.1 (7.5) | 25.7 (5.8) | 0.029 |
| HAMD-17, mean (SD) | 18.5 (4.5) | 0.6 (0.8) | <0.0001 |
| Log2 (FGF21) | 7.3 (1.3) | 6.3 (1.5) | <0.0001 |
BMI values missing for 8 HC and 22 MDD patients.