Table 5.
Association between the novel missense mutation c.551T>C and the risk of autism in genetic models
Models | Genotype | No. (%) |
OR (95% CI) | p-value | |
---|---|---|---|---|---|
Case | Control | ||||
Codominant | T/T | 81 | 148 | 1 (ref.) | - |
T/C | 1 | 2 | 0.69 (0.1‒7.7) | 0.38 | |
C/C | 26 | 0 | 96.68 | 0.001* | |
(5.8‒1,607.1) | |||||
Dominant | T/T | 81 | 148 | 1 (ref.) | - |
T/C-C/C | 27 | 2 | 24.7 | 0.001* | |
(5.7‒106.4) | |||||
Recessive | T/T-T/C | 81 | 150 | 1 (ref.) | - |
C/C | 26 | 0 | 96.68 | 0.001* | |
(5.8‒1,607.1) |
OR, odds ratio; CI, confidence interval.
p < 0.05 indicates statistical significant.