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. 2021 Dec 7;51(1):afab231. doi: 10.1093/ageing/afab231

Table 1.

Characteristics of the study population and dementia incidence rate per 1,000 person-years with 95% confidence intervals

Dementia incidence rate per 1,000 person-years
Variable Person-years Cases with dementia Rate 95% Confidence interval
Time since T2D diagnosis
Up to 1 year 15,913 816 51.28 47.88 54.92
  Up to 2 years 10,672 408 38.23 34.70 42.13
  Up to 3 years 8,966 352 39.26 35.37 43.58
  Up to 4 years 7,335 270 36.81 32.67 41.47
  Up to 5 years 5,713 246 43.06 38.00 48.79
  Up to 6 years 4,216 194 46.01 39.97 52.96
  Up to 7 years 2,815 153 54.35 46.39 63.69
  Up to 8 years 1,574 95 60.35 49.36 73.79
  More than 8 years 407 24 58.91 39.48 87.89
Diabetes severity at T2D incidence
  Less severe cases 11,407 323 28.32 25.39 31.58
  more severe 46,206 2,235 48.37 46.41 50.42
Sex
  Man 22,568 883 39.13 36.63 41.79
  Woman 35,044 1,675 47.80 45.56 50.14
Age group at T2D incidence
  65–84 53,500 2,054 38.39 36.77 40.09
  85+ 4,112 504 122.56 112.31 133.74
Treatment groups
  No ADM 40,772 1,864 45.72 43.69 47.84
  Insulin 1,071 83 77.47 62.47 96.07
  Non-insulin ADM 15,044 577 38.35 35.35 41.61
  Mixed ADM 725 34 46.88 33.50 65.61
Hypertensive diseases
  No 3,129 126 40.27 33.82 47.95
  Yes 54,484 2,432 44.64 42.90 46.45
Depression
  No 39,047 1,444 36.98 35.12 38.94
  Yes 18,566 1,114 60.00 56.58 63.63
Cerebrovascular diseases
  No 38,850 1,192 30.68 28.99 32.47
  Yes 18,763 1,366 72.80 69.04 76.77
Ischemic heart diseases
  No 26,453 953 36.03 33.81 38.39
  Yes 31,160 1,605 51.51 49.05 54.09
Atrial fibrillation and flutter
  No 43,528 1,615 37.10 35.34 38.96
  Yes 14,085 943 66.95 62.81 71.36
Obesity
  No 35,852 1,742 48.59 46.36 50.93
  Yes 21,761 816 37.50 35.01 40.16
Disorders of lipoprotein metabolism
  No 17,761 880 49.55 46.38 52.93
  Yes 39,852 1,678 42.11 40.14 44.17
Total 57,613 2,558 44.40 42.71 46.15