Table 2.
Organ-specific absorption
| Patient no. | Rituximab level pretherapy (μg/mL) | 90Y dose infused (mCi) | Total body (cGy/mCi) | Total body (cGy) | Lung (cGy/mCi) | Lung (cGy) | Liver (cGy/mCi) | Liver (cGy) |
|---|---|---|---|---|---|---|---|---|
| 11 | 66.80 | 108.34 | – | – | – | – | 4.61 | 499.44 |
| 12 | 35.60 | 82.4 | 2.27 | 187.05 | – | – | 6.7 | 552.08 |
| 13 | 40.20 | 112.65 | 3.35 | 377.38 | – | – | 21.4 | 2410.71 |
| 14 | 66.90 | 75.2 | 2.25 | 169.20 | – | – | 31.9 | 2398.88 |
| 15 | 40.30 | 122.5 | 4.27 | 523.08 | 16 | 1960 | 1.68 | 205.80 |
| Patient no. | 90Y dose infused (mCi) | Kidney (cGy/mCi) | Kidney (cGy) | Marrow (cGy/mCi) | Marrow (cGy) | Spleen (cGy/mCi) | Spleen (cGy) | |
| 11 | 108.34 | – | – | 10.1 | 1094.23 | 4.61 | 499.44 | |
| 12 | 82.4 | 3.31 | 272.74 | 13.7 | 1128.88 | – | – | |
| 13 | 112.65 | 11.2 | 1261.68 | 16.4 | 1847.46 | 16.3 | 1836.19 | |
| 14 | 75.2 | 19.6 | 1473.92 | 23.3 | 1752.16 | 117 | 8798.40 |