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. 2022 Jan 11;6(1):339–357. doi: 10.1182/bloodadvances.2021004916

Table 6.

Causes of death by cohort

Characteristic Haploidentical MSD MUD 7/8 HLA-MUD UCB
No. of deaths 132 564 625 103 130
Cause of death
ALL 64 (48) 293 (52) 240 (38) 33 (32) 40 (31)
Graft failure 1 (<1) 4 (<1) 1 (<1) 3 (3) 3 (2)
GVHD 7 (5) 81 (14) 126 (20) 25 (24) 16 (12)
Infection 28 (21) 98 (17) 126 (20) 21 (20) 30 (23)
Idiopathic pneumonia 4 (3) 5 (<1) 7 (1) 0 5 (4)
Acute respiratory distress syndrome 3 (2) 7 (1) 9 (1) 0 4 (3)
Organ failure 8 (6) 31 (5) 53 (8) 9 (9) 19 (15)
Organ toxicity 0 4 (<1) 1 (<1) 2 (2) 0
Secondary malignancy 2 (2) 4 (<1) 4 (<1) 2 (2) 2 (2)
Hemorrhage 3 (2) 4 (<1) 4 (<1) 1 (<1) 2 (2)
Accident or suicide 0 0 3 (<1) 0 0
Vascular 0 2 (<1) 1 (<1) 0 2 (2)
Other known 11 (8) 23 (4) 39 (6) 7 (7) 6 (5)
Unknown 1 (<1) 8 (1) 11 (2) 0 1 (<1)