Fig. 21.

A schematic illustration of the synthesis of Fe₃O₄@PPy@GOD NCs (a) and PT-enhanced CDT (b). (c) Proposed mechanism of Fe₃O₄@PPy@GOD NCs for PT-enhanced Fenton-based CDT. In vivo PAI and PA signals of the tumor area at various time points post-injection of Fe₃O₄@PPy@GOD NCs at 808 ​nm ​(d) and 1280 ​nm (e). (f) In vivo T₂-weighted MR images of tumor-bearing mice before and after intratumoral and intravenous injection of Fe₃O₄@PPy@GOD NCs (the red dotted circles indicate the tumor areas). Reprinted with permission of Ref. [59]. Copyright 2018 Wiley.