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. 2022 Jan 10;10(1):e003687. doi: 10.1136/jitc-2021-003687

Table 3.

Univariate and multivariate prognostic analyses for MFS

Characteristics Univariate Multivariate
N HR (95% CI) P value N HR (95% CI) P value*
Age (years) 371 1.00 (0.99 to 1.01) 0.902
Gender
 Male vs female 371 1.02 (0.70 to 1.49) 0.909
Tumor site
 Head and neck vs extremity 382 0.00 (0.00 to Inf) 0.66
 Internal trunk vs extremity 0.77 (0.50 to 1.18)
 Superficial trunk vs extremity 0.81 (0.47 to 1.40)
Depth
 Superficial vs deep 196 0.78 (0.38 to 1.61) 0.495
Pathological type
 Liposarcoma vs leiomyosarcoma 678 0.48 (0.35 to 0.67) 1.35E−06 678 0.58 (0.41 to 0.81) 1.51E−03
 Myxofibrosarcoma vs leiomyosarcoma 0.45 (0.24 to 0.86) 678 0.52 (0.27 to 0.98) 4.44E−02
 Other vs leiomyosarcoma 0.21 (0.08 to 0.57) 678 0.25 (0.09 to 0.69) 7.65E−03
 Undifferentiated sarcoma vs leiomyosarcoma 0.43 (0.30 to 0.61) 678 0.47 (0.33 to 0.68) 4.40E−05
Pathological tumor size, cm 210 1.00 (0.96 to 1.04) 0.898
Pathological FNCLCC grade
 3 vs 1–2 307 1.43 (0.95 to 2.17) 0.088
CINSARC risk
 High vs low 678 2.48 (1.87 to 3.28) 2.03E−10 678 2.19 [1.65 to 2.92) 8.14E−08
ICR classification
 1 vs 2–3 678 1.59 (1.20 to 2.08) 1.11E−03 678 1.52 (1.15 to 2.00) 3.54E−03

*Wald test.

FNCLCC, Fédération Nationale des Centres de Lutte Contre le Cancer; ICR, immunologic constant of rejection; MFS, metastasis-free survival.