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. 2022 Jan 11;10(1):e003831. doi: 10.1136/jitc-2021-003831

Table 1.

Demographics and baseline characteristics

Characteristics All patients (n=37)
Age, years, median (range) 52 (35–69)
<65 33 (89.2)
≥65 4 (10.8)
ECOG PS
0 3 (8.1)
1 33 (89.2)
Tumor type
Ovarian carcinoma 33 (89.2)
Fallopian tube carcinoma 4 (10.8)
FIGO stage at first diagnosis
I 2 (5.4)
II 6 (16.2)
III 24 (64.9)
IV 5 (13.5)
Location of metastases
Lymph node 29 (78.4)
Peritoneum 21 (56.8)
Liver 13 (35.1)
Spleen 7 (18.9)
Abdominal cavity 6 (16.2)
Lung 5 (13.5)
Number of lines of prior systemic therapy
1 4 (10.8)
2 11 (29.7)
3 10 (27.0)
4 6 (16.2)
≥5 6 (16.2)
Platinum resistant status*
Primary platinum resistant 11 (29.7)
Secondary platinum resistant 15 (40.5)
Primary platinum refractory 11 (29.7)
Previous bevacizumab use 6 (18.2)
Histologic type
Serous adenocarcinoma
High‐grade 22 (59.5)
Low-grade 1 (2.7)
Unknown 5 (13.5)
Endometrioid carcinoma 1 (2.7)
Undifferentiated carcinoma 1 (2.7)
Other epithelial ovarian cancer
High-grade adenocarcinoma 5 (13.5)
Adenocarcinoma (not otherwise specified) 2 (5.4)
PD-L1 expression †, n (%)
PD-L1 CPS≥1 8 (21.6)
PD-L1 CPS<1 11 (29.7)
Unknown 18 (48.6)

Data are n (%) unless otherwise indicated.

*Patients were categorized as primary platinum resistance (disease progression occurring ≥2 months and <6 months after completing first-line platinum therapy), secondary platinum resistance (progression ≥6 months after completing first-line platinum-based chemotherapy but <6 months after completing second-line or later-line platinum-based chemotherapy) and primary platinum refractory (progression <2 months or no response during the first-line platinum-based chemotherapy).

†Mandatory fresh biopsy or archival tissue for PD-L1 expression was not requested at enrollment.

CPS, Combined Positive Score; ECOG, Eastern Cooperative Oncology Group; FIGO, International Federation of Gynecology and Obstetrics; PD-L1, programmed death-ligand 1.