Table 2. Odds Ratios of Any Solid Tumor Diagnosis by Platelet Count Category and Time From Complete Blood Count Test to Cancer Diagnosisa.
| Platelet count percentile category by time to cancer diagnosisb | No. (%) | Odds ratio (95% CI)c | |
|---|---|---|---|
| Case patients | Control individuals | ||
| <6 mo | |||
| Very low | 19 161 (8.4) | 74 891 (11.0) | 0.87 (0.86-0.89) |
| Low | 27 308 (12.0) | 106 707 (15.6) | 0.87 (0.86-0.89) |
| Medium | 98 480 (43.3) | 336 232 (49.2) | 1 [Reference] |
| High | 38 372 (16.9) | 99 539 (14.6) | 1.32 (1.30-1.34) |
| Very high | 44 344 (19.5) | 65 626 (9.6) | 2.32 (2.28-2.35) |
| 6 to <12 mo | |||
| Very low | 14 870 (10.1) | 48 700 (11.0) | 0.95 (0.93-0.97) |
| Low | 20 716 (14.0) | 69 561 (15.7) | 0.93 (0.91-0.95) |
| Medium | 70 078 (47.4) | 219 039 (49.4) | 1 [Reference] |
| High | 23 209 (15.7) | 64 288 (14.5) | 1.13 (1.11-1.15) |
| Very high | 19 038 (12.9) | 42 145 (9.5) | 1.41 (1.39-1.44) |
| 12 to <24 mo | |||
| Very low | 22 086 (10.2) | 70 743 (10.9) | 0.95 (0.93-0.96) |
| Low | 32 018 (14.7) | 103 336 (15.9) | 0.94 (0.93-0.95) |
| Medium | 106 239 (48.9) | 322 348 (49.5) | 1 [Reference] |
| High | 32 952 (15.2) | 94 872 (14.6) | 1.05 (1.04-1.07) |
| Very high | 23 942 (11.0) | 60 412 (9.3) | 1.20 (1.18-1.22) |
| 24 to <60 mo | |||
| Very low | 27 116 (10.1) | 87 869 (10.9) | 0.93 (0.92-0.95) |
| Low | 40 852 (15.2) | 127 941 (15.9) | 0.97 (0.95-0.98) |
| Medium | 132 330 (49.4) | 400 393 (49.8) | 1 [Reference] |
| High | 40 363 (15.1) | 115 881 (14.4) | 1.05 (1.04-1.07) |
| Very high | 27 481 (10.2) | 72 342 (9.0) | 1.15 (1.13-1.17) |
| 60-120 mo | |||
| Very low | 15 744 (10.1) | 49 761 (10.7) | 0.96 (0.94-0.98) |
| Low | 23 750 (15.3) | 74 880 (16.1) | 0.96 (0.94-0.97) |
| Medium | 76 963 (49.5) | 232 828 (49.9) | 1 [Reference] |
| High | 23 340 (15.0) | 66 787 (14.3) | 1.06 (1.04-1.08) |
| Very high | 15 655 (10.1) | 42 100 (9.0) | 1.13 (1.10-1.15) |
a
Liver cancer was excluded.
b
Platelet count percentile categories were defined as follows: very low (≤10th percentile), low (>10th to 25th percentile), medium (>25th to <75th percentile), high (75th to <90th percentile), and very high (≥90th percentile).
c
P < .001 for all.