Fig. 4.
SGB121 improved HFD-induced pathologies in mouse brain. (A) Western blots for total and phosphorylated tau protein. (B) Western blots for beta-amyloid protein. (C) HFD-induced changes on tau protein in mouse brain. Phosphorylated tau were analyzed by IHC method. (D) GFAP staining in white matter (corpus callosum) (200×). Actin was used as loading control. ∗ indicates p<0.05 versus ND, ∗∗∗ indicates p<0.001 versus ND, # indicates p<0.05 versus HFD, ## indicates p<0.01 versus HFD. Scale bar,100 μm.