TABLE 3.
Summary of results
| Isolate | Speciesa | PFGE pattern
|
No. of plasmids
|
OspA serotype | % Arthritogenicityb | Recovery from:
|
IL-6 secretion | Pathogenicityd | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MluI | SmaI | 60–40 kb | 39–30 kb | 29–20 kb | <20 kb | EPB | Organsc | ||||||
| PV1 | S | MLb13 | SMb1 | 2 | 2 | 1 | 0 | 1 | 0 | − | B | + | LP |
| PV2 | S | MLb2 | SMb2 | 2 | 2 | 1 | 0 | 1 | 0 | − | − | − | NP |
| PV3 | S | MLb2 | SMb1 | 3 | 0 | 1 | 0 | 1 | 25 | − | − | − | LP |
| PV4 | G | MLg2 | SMg1 | 2 | 1 | 2 | 0 | 5 | 100 | + | B, S, H, Br | ++ | P |
| PV5 | G | MLg2 | SMg2 | 4 | 0 | 2 | 0 | 5 | 25 | − | B | − | LP |
| PV6 | G | MLg2 | SMg1 | 3 | 2 | 2 | 0 | 5 | 100 | + | B, S, H, Br, K, L | +++ | P |
| PV7 | V | MLv1 | SMv1 | 2 | 0 | 1 | 0 | NDe | 0 | − | − | − | NP |
| PV8 | L | ND | ND | ND | ND | ND | ND | ND | 0 | − | − | − | NP |
| CL1 | G | MLg2 | SMg3 | 3 | 0 | 2 | 0 | 8 | 100 | + | B | ++ | P |
| Rio1 | G | MLg2 | SMg1 | ND | ND | ND | ND | 5 | 25 | + | B, S | − | P |
| Rio2 | G | MLg2 | SMg3 | 2 | 1 | 2 | 0 | 3 | 100 | + | − | + | LP |
| Rio3 | G | MLg2 | SMg2 | 3 | 0 | 2 | 0 | 5 | 100 | + | S, H | ++ | P |
| Rio4 | G | MLg2 | SMg4 | 2 | 1 | 1 | 1 | 6 | 100 | + | B, H, K | + | P |
| Rio5 | G | MLg2 | SMg2 | 2 | 2 | 1 | 0 | 6 | 100 | + | B, K | +++ | P |
| Rio6 | V | MLv1 | SMv1 | 1 | 0 | 1 | 0 | ND | 25 | + | B, K | − | P |
a
S, B. burgdorferi sensu stricto; G, B. garinii; V, B. valaisiana; L, B. lusitaniae.
b
Percentage based on 20 mice.
c
B, urinary bladder; S, spleen; H, heart; Br, brain; K, kidney; L, liver.
d
NP, nonpathogenic; LP, low pathogenicity; P, pathogenic.
e
ND, not determined.