Haloperidol and clozapine do not alter SR and DAAO expression. Mice were divided into 4 groups (saline vehicle, acetic acid vehicle, haloperidol, and clozapine). Because saline vehicle (n = 4) and acetic acid vehicle (n = 5) group were not significantly different, we combined them into a single vehicle group. Protein levels of serine racemase (SR; A, C, E) and D-amino acid oxidase (DAAO; B, D, F) were measured in the frontal cortex (A, B), striatum (C, D) and hippocampus (E, F) from mice treated with vehicle (n = 9; white bars), clozapine (n = 8; black bars), or haloperidol (n = 7; stripe bars). Values are expressed as the optical density (OD) normalized to vehicle treated values (% vehicle). One-way ANOVA was used for analysis. All values represent the mean ± SEM.