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. 2021 Dec 17;23(2):154. doi: 10.3892/etm.2021.11077

Figure 1.

Figure 1

Effects of KDM2B on pathological changes in myocardial ischemia-reperfusion injury in rats. In total, six groups, including the sham control group, model group, si-KDM2B group, siRNA NC group, KDM2B overexpression group and overexpression NC group, were included in the present study. H&E staining was applied to determine the pathological changes. Arrows indicate sites of necrosis and neutrophil infliltration. Scale bars, 50 µm. AAV, adeno-associated virus; KDM2B, lysine-specific demethylase 2B; NC, negative control; si/siRNA, small interfering RNA; si-KDM2B, AAV-siKDM2B; siRNA NC, AAV-siRNA scrambled negative control.