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. 2022 Jan 12;10(1):e00991-21. doi: 10.1128/spectrum.00991-21

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Copyright © 2022 Wen et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Bacterial growth curve and bactericidal effect analysis of GA (15:1) against E. faecalis (16C1) and MRSA HaMRSA20. (A, B) Impact of GA (15:1) at different concentrations (1/4×, 1/2×, and 1× MIC) on the bacterial growth of vancomycin-intermediate E. faecalis 16C1 and MRSA HaMRSA20 planktonic cells. (C, D) Time-kill assay of GA (15:1) with 1×, 2×, 4×, and 8× MIC against vancomycin-intermediate E. faecalis isolate 16C1 and MRSA HaMRSA20 cells at exponential phase. Data are presented as mean values ± standard deviations (SD). The control concentration (for both ampicillin and vancomycin) was 4× MIC.