TABLE 5.
Neutralization of sera-purified IgGs from immunized rabbits
| Immunogen | Rabbit | IC50 (μg/ml) of: |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| VI 191, subtype A, tier 2 | AC10.029, subtype B, tier 2 | NL4-3, subtype B, tier 1A | 92BR025, subtype C, tier 1B | 92UG024, subtype D, tier 2 | CM244, subtype AE, tier 2 | 887-SOS-T pseudovirusa | 936-SOS-T pseudovirus | ||
| 887-SOS-T vLP | 1769 | >500 | >500 | >500 | >500 | >500 | >500 | >200 | ND |
| 1775 | >500 | >500 | >500 | >500 | >500 | >500 | >200 | ND | |
| 1776 | >100 | >100 | >100 | >100 | >100 | >100 | >200 | ND | |
| 1777 | >100 | >100 | >100 | >100 | >100 | >100 | >200 | ND | |
| 887 SOSIP | 1768 | >500 | >500 | >500 | >500 | >500 | >500 | >200 | ND |
| 1772 | >500 | >500 | >500 | >500 | >500 | >500 | >200 | ND | |
| 1774 | >100 | >100 | >100 | >100 | >100 | >100 | >200 | ND | |
| 1778 | >100 | >100 | >100 | >100 | >100 | >100 | >200 | ND | |
| 936-SOS-T vLP | 1783 | >200 | >200 | >200 | >200 | >200 | >200 | ND | >500 |
| 1784 | >200 | >200 | >200 | >200 | >200 | >200 | ND | >500 | |
| 1785 | >200 | >200 | >200 | >200 | >200 | >200 | ND | >500 | |
| 1786 | >200 | >200 | >200 | >200 | >200 | >200 | ND | >500 | |
| 936 SOSIP | 1787 | >200 | >200 | >200 | >200 | >200 | >200 | ND | >500 |
| 1788 | >200 | >200 | >200 | >200 | >200 | >200 | ND | >500 | |
| 1789 | >200 | >200 | >200 | >200 | >200 | >200 | ND | >500 | |
| 1790 | >200 | >200 | >200 | >200 | >200 | >200 | ND | >500 | |
aND, not determined.