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. 2022 Jan 12;8(2):eabk1789. doi: 10.1126/sciadv.abk1789

Fig. 7. Disruptions of human RAD51AP2 C terminus abolish the interaction with RAD51.

Fig. 7.

(A) Schematic of the tagged human proteins. The FLAG tag is indicated by the yellow box, and GFP tags are indicated by the green boxes. The amino acids altered after the Mut-2 frameshift mutation are indicated by the purple box. (B) Co-IP assays with transfected HEK293T cells, showing that the interaction with RAD51 is disrupted for the human RAD51AP2 variants lacking its C-terminal 33 amino acids or SRPI and for an RAD51AP2 variant, Mut-2 (p.R1131Lfs*19, identified in case 241)”.